Preheat oven to 400°. Spray a large rimmed baking sheet with cooking spray.
In a large bowl, stir together sweet peppers, zucchini, onion, oil, oregano, and ½ teaspoon salt. Place in an even layer on prepared pan.
Bake for 30 minutes. Push vegetables to one side of pan.
In a small bowl, stir together brown sugar, paprika, black pepper, red pepper, and remaining 1 teaspoon salt. Season catfish with sugar mixture. Wrap each fillet with 2 slices bacon, securing with wooden picks, if necessary. Place in an even layer on other side of pan.
Bake for 15 minutes. Increase oven temperature to broil. Broil until bacon is crisp, 3 to 5 minutes. Garnish with oregano, if desired.
Recipe by Taste of the South at https://tasteofthesouthmagazine.com/bacon-wrapped-catfish/